Pathology Poster - Keratohyaline Granules

 Dr Sampurna Roy MD



 Keratohyaline granules




KERATOHYALINE: refers to granules of different sizes and shapes that appear purple in sections stained by hematoxylin and eosin, and that are situated in the granular zone of the surface epidermis; the infundibular epidermis, and the sebaceous duct. Products of keratohyaline granules are essential to normal cornification of those epithelial structures. An increased quantity of abnormal keratohyaline granules is found in a variety of diseases (i.e., in the infundibula of verrucae vulgaris, lichen planopilaris, and prurigo nodularis





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