Pathology Poster - Metanephric Adenoma of the Kidney
Dr Sampurna Roy MD
Macroscopically, revealed a homogenous tan or yellowish-white colour cut surface and the encapsulated tumour generally formed well-circumscribed mass.
Microscopically,the tumour was composed of variable proportions of cells proliferated with formation of small glomeruloid bodies.
Tumours cells had uniformly small and indistinct nucleoli, and scanty cytoplasm.
Immunohistochemical staining revealed most tumor cells were positive expression of WT-1
Immunohistochemical staining of tumor cells were positive for CD57
Metanephric adenoma is a rare renal epithelial tumour ( 0.2% of all adult renal epithelial neoplasms).
The majority of cases occurs in patients 50–60 years of age and is seen predominantly in females by a 2:1 ratio.
Among renal lesions, it has the highest incidence (12%) of polycythemia.
The differential diagnosis includes epithelial-predominant Wilms tumor and the solid variant of papillary renal cell carcinoma.
- Patel RD, Frederick L, Kohler T, Schwartz B. A Case of a Metanephric Adenoma of the Kidney Surgically Treated with Robot-Assisted Laparoscopic Partial Nephrectomy. Case Reports in Urology. 2013;2013:703859. doi:10.1155/2013/703859.