Pathology Poster - Paget Cell and Paget Pattern

  Dr Sampurna Roy MD

 

 

 Paget cell ; Paget Pattern

 

 

 

Paget Cell :

Specific for mammary Paget’s disease and extramammary Paget’s disease, is typified by a large, round, or plump oval nucleus and pale-staining cytoplasm, the latter being more abundant in extramammary Paget’s disease because there it is replete with acid mucopolysaccharides that are demonstrable by staining with hematoxylin and eosin and better yet with stains specialized for them.

Paget cells of mammary Paget’s disease and extramammary Paget’s disease have several attributes in common, but they are dissimilar, just as are mammary Paget’s disease and extramammary Paget’s diseases themselves, despite the fact that they share the word "mammary" and the name "Paget’s disease."

 

Paget Pattern:

This pattern is characterized by scatter of cells constituent of mammary Paget’s disease and extramammary Paget’s disease throughout an epithelium, usually epidermal but also adnexa.

 


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