Pathology Poster and Titbits- Pleomorphic Adenoma of the Nose
Dr Sampurna Roy MD
"Intranasal pleomorphic adenoma usually originates from glands of the nasal septum mucosa, although most of the salivary glands are located in the lateral nasal wall and concha.
There are some suggestions that the septal origin of the pleomorphic adenoma could be secondary to misplaced embryonic ectoderm cells, a remnant of the vomeronasal organ or could be induced by a viral infection.
This tumour occurs in the third to the sixth decades of life.
The presenting symptoms are usually nasal obstruction and occasionally bleeding.
Nasal pleomorphic adenomas differ from major salivary gland pleomorphic adenomas as they contain higher cellularity and epithelial component with a low stromal one. These tumours also lack a capsule."