Wake up Sleeping Beauty! Sad ending of a fairy tale - Kleine–Levin Syndrome (Sleeping Beauty Syndrome)

 Dr Sampurna Roy MD

So you have slept all day ( almost 18 hours) and still feeling sleepy and tired.

You are in a dream-like state and experiencing life outside of your own body.

You are eating too much food and behaving badly with everyone.

You are having difficulty paying attention, remembering, and making decisions. 

You are angry, confused and disorientated. 

It is not your fault.

You are probably suffering from an exceedingly rare neurological disease,  Kleine-Levin syndrome (Sleeping Beauty Syndrome).

This sleeping disorder is characterized by recurrent episodes of hypersomnia (excessive daytime sleepiness) and hyperphagia (rapid consumption of a large amount of food), usually with onset in early adolescence in males but occasionally in later life and in women.

It is a very rare condition (around one to two cases per million).

"Kleine-Levin syndrome was possibly first reported by Brierre de Bosmont in 1862. 

The disorder received its name from Willi Kleine who, in 1925, reported a series of cases of periodic hypersomnia and Max Levin who described a case of periodic hypersomnia and excessive appetite in 1930.  In their classic paper "The Syndrome of Periodic Somnolence and Morbid Hunger" Critchley and Hoffman described the cases of two men in their 20s who developed hypersomnia and hyperphagia, with symptoms lasting days to weeks at a time and recurring every few months."

This fairy tale has a sad ending.


Kleine-Levine syndrome: a review

The Kleine-Levin Syndrome: A Rare Disease with Often Delayed Diagnosis—A Report of Two Cases in the Department of Neurology of the University Hospital of Cocody (Côte d'Ivoire)

Image courtesy - Pixabay

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